Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Circulating influenza viruses evade neutralization in their human hosts by acquiring escape mutations at epitopes of prevalent antibodies. A goal for next-generation influenza vaccines is to reduce escape likelihood by selectively eliciting antibodies recognizing conserved surfaces on the viral hema...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Raymond, Donald D., Bajic, Goran, Ferdman, Jack, Suphaphiphat, Pirada, Settembre, Ethan C., Moody, M. Anthony, Schmidt, Aaron G., Harrison, Stephen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776812/
https://ncbi.nlm.nih.gov/pubmed/29255041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715471115
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