Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses, Strongyloides stercoralis hyperinfection in NSG mice

Strongyloides stercoralis hyperinfection causes high mortality rates in humans, and, while hyperinfection can be induced by immunosuppressive glucocorticoids, the pathogenesis remains unknown. Since immunocompetent mice are resistant to infection with S. stercoralis, we hypothesized that NSG mice, w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Patton, John B., Bonne-Année, Sandra, Deckman, Jessica, Hess, Jessica A., Torigian, April, Nolan, Thomas J., Wang, Zhu, Kliewer, Steven A., Durham, Amy C., Lee, James J., Eberhard, Mark L., Mangelsdorf, David J., Lok, James B., Abraham, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776800/
https://ncbi.nlm.nih.gov/pubmed/29203662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712235114
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