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Acid-Sensing Ion Channels Contribute to Neurotoxicity

Acidosis that occurs under pathological conditions not only affects intracellular signaling molecules, but also directly activates a unique family of ligand-gated ion channels: acid-sensing ion channels (ASICs). ASICs are widely expressed throughout the central and peripheral nervous systems and pla...

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Detalhes bibliográficos
Publicado no:Transl Stroke Res
Main Authors: Chu, Xiang-Ping, Grasing, Kenneth A., Wang, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776693/
https://ncbi.nlm.nih.gov/pubmed/24323724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-013-0305-y
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