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Chitosan temperature-sensitive gel loaded with drug microspheres has excellent effectiveness, biocompatibility and safety as an ophthalmic drug delivery system

In the present study, a temperature-sensitive gel composed of chitosan, carboxymethyl chitosan and glycerophosphate was prepared and loaded with chitosan microspheres encapsulating levofloxacin. The bioavailability of levofloxacin and the safety of this novel opthalmic drug delivery formulation were...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Kong, Xiaoying, Xu, Wenhua, Zhang, Cuiping, Kong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776523/
https://ncbi.nlm.nih.gov/pubmed/29434728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5586
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