Brucella Downregulates Tumor Necrosis Factor-α to Promote Intracellular Survival via Omp25 Regulation of Different MicroRNAs in Porcine and Murine Macrophages

Brucella spp. impedes the production of pro-inflammatory cytokines by its outer membrane protein Omp25 in order to promote survival and immune evasion. However, how Omp25 regulates tumor necrosis factor (TNF-α) expression in different mammalian macrophages remains unclear. In this study, we investig...

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Udgivet i:Front Immunol
Main Authors: Luo, Xiaomao, Zhang, Xiujuan, Wu, Xingchen, Yang, Xuefeng, Han, Cong, Wang, Zhengyu, Du, Qian, Zhao, Xiaomin, Liu, Shan-Lu, Tong, Dewen, Huang, Yong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776175/
https://ncbi.nlm.nih.gov/pubmed/29387067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.02013
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