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Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain

Neuronal metal ions such as zinc are essential for brain function. In particular synaptic processes are tightly related to metal and protein homeostasis, for example through extracellular metal-binding proteins. One such protein is neuronal S100B, a calcium and zinc binding damage-associated molecul...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Hagmeyer, Simone, Cristóvão, Joana S., Mulvihill, John J. E., Boeckers, Tobias M., Gomes, Cláudio M., Grabrucker, Andreas M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776125/
https://ncbi.nlm.nih.gov/pubmed/29386995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00456
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