Elevated Serum Lysophosphatidylcholine in Patients with Systemic Lupus Erythematosus Impairs Phagocytosis of Necrotic Cells In Vitro

OBJECTIVES: Impaired clearance of dying and dead cells by professional and amateur phagocytes plays a crucial role in the etiology of systemic lupus erythematosus (SLE). While dying, cells expose and release a plethora of eat-me and find-me signals to ensure their timely removal before entering the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Grossmayer, Gerhard E., Keppeler, Hildegard, Boeltz, Sebastian, Janko, Christina, Rech, Jürgen, Herrmann, Martin, Lauber, Kirsten, Muñoz, Luis E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776078/
https://ncbi.nlm.nih.gov/pubmed/29387051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01876
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