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X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from Aβ(16–36)
The assembly of the β-amyloid peptide, Aβ, into soluble oligomers is associated with neurodegeneration in Alzheimer's disease. The Aβ oligomers are thought to be composed of β-hairpins. Here, the effect of shifting the residue pairing of the β-hairpins on the structures of the oligomers that fo...
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| Publicado no: | Org Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776032/ https://ncbi.nlm.nih.gov/pubmed/28683555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01445 |
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