Interferon Regulatory Factor 6 Controls Proliferation of Keratinocytes From Children With Van der Woude Syndrome

OBJECTIVE: Interferon Regulatory Factor 6 (IRF6) is critical for craniofacial development, epidermal differentiation, and tissue repair. IRF6 mutations cause Van der Woude Syndrome (VWS) and Popliteal Pterygium Syndrome. Individuals with VWS exhibit craniofacial anomalies, including cleft lip and pa...

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Bibliographic Details
Published in:Cleft Palate Craniofac J
Main Authors: Hixon, Katherine, Rhea, Lindsey, Standley, Jennifer, Canady, Frank J., Canady, John W., Dunnwald, Martine
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776006/
https://ncbi.nlm.nih.gov/pubmed/27115562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1597/15-275
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