Are minor alleles more likely to be risk alleles?

BACKGROUND: Genome-wide association studies (GWASs) have revealed relationships between over 57,000 genetic variants and diseases. However, unlike Mendelian diseases, complex diseases arise from the interplay of multiple genetic and environmental factors. Natural selection has led to a high tendency...

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Podrobná bibliografie
Vydáno v:BMC Med Genomics
Hlavní autoři: Kido, Takashi, Sikora-Wohlfeld, Weronika, Kawashima, Minae, Kikuchi, Shinichi, Kamatani, Naoyuki, Patwardhan, Anil, Chen, Richard, Sirota, Marina, Kodama, Keiichi, Hadley, Dexter, Butte, Atul J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775585/
https://ncbi.nlm.nih.gov/pubmed/29351777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0322-5
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