Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K(+) channel Kv1.5

The voltage-gated K(+) channel has key roles in the vasculature and in atrial excitability and contributes to apoptosis in various tissues. In this study, we have explored its regulation by carbon monoxide (CO), a product of the cytoprotective heme oxygenase enzymes, and a recognized toxin. CO inhib...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Al-Owais, Moza M, Hettiarachchi, Nishani T, Boyle, John P, Scragg, Jason L, Elies, Jacobo, Dallas, Mark L, Lippiat, Jon D, Steele, Derek S, Peers, Chris
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775415/
https://ncbi.nlm.nih.gov/pubmed/29095440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.568
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