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Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes
Discovery of robust diagnostic or prognostic biomarkers is a key to optimizing therapeutic benefit for select patient cohorts - an idea commonly referred to as precision medicine. Most discovery studies to derive such markers from high-dimensional transcriptomics datasets are weakly powered with sam...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5775343/ https://ncbi.nlm.nih.gov/pubmed/29352257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19635-0 |
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