Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model

Survivors of Ebola virus infection may become subclinically infected, but whether animal models recapitulate this complication is unclear. Using histology in combination with immunohistochemistry and in situ hybridization in a retrospective review of a guinea pig confirmation-of-virulence study, we...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cooper, Timothy K., Huzella, Louis, Johnson, Joshua C., Rojas, Oscar, Yellayi, Sri, Sun, Mei G., Bavari, Sina, Bonilla, Amanda, Hart, Randy, Jahrling, Peter B., Kuhn, Jens H., Zeng, Xiankun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775334/
https://ncbi.nlm.nih.gov/pubmed/29352230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19638-x
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