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Brownian dynamic study of an enzyme metabolon in the TCA cycle: Substrate kinetics and channeling
Malate dehydrogenase (MDH) and citrate synthase (CS) are two pacemaking enzymes involved in the tricarboxylic acid (TCA) cycle. Oxaloacetate (OAA) molecules are the intermediate substrates that are transferred from the MDH to CS to carry out sequential catalysis. It is known that, to achieve a high...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5775167/ https://ncbi.nlm.nih.gov/pubmed/29094409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3338 |
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