EphA2/Ephrin-A1 Mediate Corneal Epithelial Cell Compartmentalization via ADAM10 Regulation of EGFR Signaling

PURPOSE: Progenitor cells of the limbal epithelium reside in a discrete area peripheral to the more differentiated corneal epithelium and maintain tissue homeostasis. What regulates the limbal–corneal epithelial boundary is a major unanswered question. Ephrin-A1 ligand is enriched in the limbal epit...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kaplan, Nihal, Ventrella, Rosa, Peng, Han, Pal-Ghosh, Sonali, Arvanitis, Constadina, Rappoport, Joshua Z., Mitchell, Brian J., Stepp, Mary Ann, Lavker, Robert M., Getsios, Spiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Cornea
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774870/
https://ncbi.nlm.nih.gov/pubmed/29351356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22941
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