Kappa opioid receptors regulate hippocampal synaptic homeostasis and epileptogenesis

OBJECTIVE: Homeostatic synaptic plasticity (HSP) serves as a gain control mechanism at CNS synapses, including those between the dentate gyrus (DG) and CA3. Improper circuit control of DG-CA3 synapses is hypothesized to underlie epileptogenesis. Here, we sought to (1) identify compounds that prefere...

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Bibliografski detalji
Izdano u:Epilepsia
Glavni autori: Queenan, Bridget N., Dunn, Raymond L., Santos, Victor R., Feng, Yang, Huizenga, Megan N., Hammack, Robert J., Vicini, Stefano, Forcelli, Patrick A., Pak, Daniel T.S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774867/
https://ncbi.nlm.nih.gov/pubmed/29114861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13941
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