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Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model

Cryptosporidiosis causes life-threatening diarrhea in infants, but the best available treatment is only modestly efficacious. Rodents infected with relevant Cryptosporidium species do not develop diarrhea, which complicates drug development. Cryptosporidium parvum infection of dairy calves, however,...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Stebbins, Erin, Jumani, Rajiv S., Klopfer, Connor, Barlow, John, Miller, Peter, Campbell, Mary A., Meyers, Marvin J., Griggs, David W., Huston, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774826/
https://ncbi.nlm.nih.gov/pubmed/29309415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006183
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