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Decreased α-cell mass and early structural alterations of the exocrine pancreas in patients with type 1 diabetes: An analysis based on the nPOD repository

BACKGROUND AND AIMS: Abnormal glucagon secretion and functional alterations of the exocrine pancreas have been described in patients with type 1 diabetes (T1D), but their respective anatomical substrata have seldom been investigated. Our aim was to develop an automated morphometric analysis process...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bonnet-Serrano, Fidéline, Diedisheim, Marc, Mallone, Roberto, Larger, Etienne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774815/
https://ncbi.nlm.nih.gov/pubmed/29352311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191528
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