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Mutant loxP vectors for selectable marker recycle and conditional knock-outs

BACKGROUND: Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used as a model for gene knock-outs due to its high targeted integration activity. Disruption of multiple genes and co...

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Autors principals: Arakawa, Hiroshi, Lodygin, Dimitry, Buerstedde, Jean-Marie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC57747/
https://ncbi.nlm.nih.gov/pubmed/11591226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-1-7
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