Decreased MiR-17 in glioma cells increased cell viability and migration by increasing the expression of Cyclin D1, p-Akt and Akt

BACKGROUND: The activating mutations of micro RNA (miR)-17 have been revealed in tumors such as human non-Hodgkin's lymphoma and T cell leukemia. However, it is unclear about the role of miR-17 in glioma cells. The current study aimed to investigate effects of miR-17 mimics or inhibitor on the...

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Publicat a:PLoS One
Autors principals: Sun, Guangwei, SiMa, Guozhong, Wu, Chunhui, Fan, Yongzhong, Tan, Yong, Wang, Zhong, Cheng, Gang, Li, Jie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774692/
https://ncbi.nlm.nih.gov/pubmed/29351283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190515
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