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Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments

Edward Jenner and his contemporaries believed that his variolae vaccinae originated in horses and molecular analyses show that modern vaccinia virus (VACV) strains share common ancestry with horsepox virus (HPXV). Given concerns relating to the toxicity of modern VACV vaccines, we asked whether an H...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Noyce, Ryan S., Lederman, Seth, Evans, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774680/
https://ncbi.nlm.nih.gov/pubmed/29351298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188453
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