Fibroblast growth factor receptor 1 amplification in laryngeal squamous cell carcinoma

Fibroblast growth factor receptor 1 (FGFR1) has been noted to be amplified in a variety of squamous cell carcinomas (SCCa) of the head, neck, and lung and increased copy number (CN) is a predictor of poor outcomes. FGFR1 is a therapeutic target for lung SCCa and inhibition therapy is currently in cl...

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Bibliographic Details
Published in:PLoS One
Main Authors: Monico, Jesus, Miller, Brandon, Rezeanu, Luminita, May, Warren, Sullivan, Donna C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774678/
https://ncbi.nlm.nih.gov/pubmed/29351293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186185
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