Benzodiazepine Augmented γ-Amino-Butyric Acid Signaling Increases Mortality From Pneumonia in Mice

OBJECTIVES: Benzodiazepines are used for treating anxiety, epilepsy, muscle spasm, alcohol withdrawal, palliation, insomnia, and sedation as they allosterically modulate γ-amino-butyric acid type A (GABA(A)) receptors. Despite widespread use, the importance and mechanism of their immune side-effects...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: Sanders, Robert D., Godlee, Alexandra, Fujimori, Toshifumi, Goulding, John, Xin, Gang, Salek-Ardakani, Samira, Snelgrove, Robert J., Ma, Daqing, Maze, Mervyn, Hussell, Tracy
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774585/
https://ncbi.nlm.nih.gov/pubmed/23478657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31827c0c8d
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