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Preclinical study on hypoxic radiosensitizing effects of glycididazole in comparison with those of doranidazole in vitro and in vivo

To overcome the radioresistance of hypoxic cells in solid tumor, numerous types of radiosensitizers specifically against them have been developed. Glycididazole has a chemical structure in which two metronidazole forms are combined, and is widely used as a hypoxic radiosensitizer in China. However,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Yasui, Hironobu, Kubota, Nobuo, Nishizumi, Junko, Sakai, Yuri, Yamamori, Tohru, Inanami, Osamu
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774408/
https://ncbi.nlm.nih.gov/pubmed/29434899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7481
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