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Metformin synergizes with rapamycin to inhibit the growth of pancreatic cancer in vitro and in vivo

Previous studies have suggested that metformin may improve the survival rate of patients with pancreatic cancer (PC) by regulating the adenosine monophosphate-activated protein kinase/mammalian target of rapamycin (mTOR) signaling pathway. Rapamycin specifically targets mTOR. In the present study, t...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Zhang, Jia-Wei, Zhao, Fan, Sun, Qing
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774390/
https://ncbi.nlm.nih.gov/pubmed/29434877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7444
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