The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species

Neutrophils are essential effector cells of the innate immune system that have recently been recognized as thyroid hormone (TH) target cells. Cellular TH bioavailability is regulated by the deiodinase enzymes, which can activate or inactivate TH. We have previously shown that the TH inactivating enz...

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Veröffentlicht in:Endocrinology
Hauptverfasser: van der Spek, Anne H., Jim, Kin Ki, Karaczyn, Aldona, van Beeren, Hermina C., Ackermans, Mariëtte T., Darras, Veerle M., Vandenbroucke-Grauls, Christina M. J. E., Hernandez, Arturo, Brouwer, Matthijs C., Fliers, Eric, van de Beek, Diederik, Boelen, Anita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2017
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774253/
https://ncbi.nlm.nih.gov/pubmed/29186449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00666
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