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Co-infecting microbes dramatically alter pathogen gene essentiality during polymicrobial infection
Identifying genes required by pathogens during infection is critical for antimicrobial development. Here, we used a Monte Carlo simulation-based method to analyze high-throughput transposon sequencing data to determine the role of infection site and co-infecting microbes on the in vivo ‘essential’ g...
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| Publicat a: | Nat Microbiol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774221/ https://ncbi.nlm.nih.gov/pubmed/28555625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.79 |
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