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Co-infecting microbes dramatically alter pathogen gene essentiality during polymicrobial infection

Identifying genes required by pathogens during infection is critical for antimicrobial development. Here, we used a Monte Carlo simulation-based method to analyze high-throughput transposon sequencing data to determine the role of infection site and co-infecting microbes on the in vivo ‘essential’ g...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Ibberson, Carolyn B., Stacy, Apollo, Fleming, Derek, Dees, Justine L., Rumbaugh, Kendra, Gilmore, Michael S., Whiteley, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774221/
https://ncbi.nlm.nih.gov/pubmed/28555625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.79
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