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Somatic evolutionary timings of driver mutations
BACKGROUND: A unified analysis of DNA sequences from hundreds of tumors concluded that the driver mutations primarily occur in the earliest stages of cancer formation, with relatively few driver mutation events detected in the late-arising subclones. However, emerging evidence from the sequencing of...
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| Udgivet i: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774140/ https://ncbi.nlm.nih.gov/pubmed/29347918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3977-y |
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