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Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse

BACKGROUND: Catastrophic chromosomal event known as chromothripsis was proven to be a significant hallmark of poor prognosis in several cancer diseases. While this phenomenon is very rare in among multiple myeloma (MM) patients, its presence in karyotype is associated with very poor prognosis. CASE...

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Podrobná bibliografie
Vydáno v:Mol Cytogenet
Hlavní autoři: Smetana, Jan, Oppelt, Jan, Štork, Martin, Pour, Luděk, Kuglík, Petr
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774134/
https://ncbi.nlm.nih.gov/pubmed/29375670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-018-0357-5
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