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Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse

BACKGROUND: Catastrophic chromosomal event known as chromothripsis was proven to be a significant hallmark of poor prognosis in several cancer diseases. While this phenomenon is very rare in among multiple myeloma (MM) patients, its presence in karyotype is associated with very poor prognosis. CASE...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Principais autores: Smetana, Jan, Oppelt, Jan, Štork, Martin, Pour, Luděk, Kuglík, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774134/
https://ncbi.nlm.nih.gov/pubmed/29375670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-018-0357-5
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