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Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug‐induced toxicity in vitro

BACKGROUND AND PURPOSE: SQSTM1/p62 is a multifunctional, stress‐induced, scaffold protein involved in multiple cellular processes including autophagic clearance, regulation of inflammatory responses and redox homeostasis. Its altered function has been associated with different human pathologies, suc...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Alegre, Fernando, Moragrega, Ángela B, Polo, Miriam, Marti‐Rodrigo, Alberto, Esplugues, Juan V, Blas‐Garcia, Ana, Apostolova, Nadezda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773949/
https://ncbi.nlm.nih.gov/pubmed/29148034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14093
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