Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no effective treatments. Numerous RNA-binding proteins (RBPs) have been shown to be altered in ALS, with mutations in 11 RBPs causing familial forms of the disease, and 6 more RBPs showing abnormal expression/distrib...

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Veröffentlicht in:Acta Neuropathol
Hauptverfasser: Bakkar, Nadine, Kovalik, Tina, Lorenzini, Ileana, Spangler, Scott, Lacoste, Alix, Sponaugle, Kyle, Ferrante, Philip, Argentinis, Elenee, Sattler, Rita, Bowser, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773659/
https://ncbi.nlm.nih.gov/pubmed/29134320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1785-8
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