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Noise-induced bistability in the fate of cancer phenotypic quasispecies: a bit-strings approach

Tumor cell populations are highly heterogeneous. Such heterogeneity, both at genotypic and phenotypic levels, is a key feature during tumorigenesis. How to investigate the impact of this heterogeneity in the dynamics of tumors cells becomes an important issue. Here we explore a stochastic model desc...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Sardanyés, Josep, Alarcón, Tomás
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773630/
https://ncbi.nlm.nih.gov/pubmed/29348614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19552-2
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