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Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation
SALM5, a synaptic adhesion molecule implicated in autism, induces presynaptic differentiation through binding to the LAR family receptor protein tyrosine phosphatases (LAR-RPTPs) that have been highlighted as presynaptic hubs for synapse formation. The mechanisms underlying SALM5/LAR-RPTP interactio...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5773555/ https://ncbi.nlm.nih.gov/pubmed/29348579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02414-2 |
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