Variation at position 350 in the Chikungunya virus 6K-E1 protein determines the sensitivity of detection in a rapid E1-antigen test

Chikungunya virus (CHIKV), a mosquito-borne pathogen, consists of three genotypes: East/Central/South African (ECSA), West African (WA), and Asian. Although a current rapid immunochromatographic (IC) test detecting CHIKV E1-antigen showed high sensitivity to ECSA-genotype viruses, it showed poor per...

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Published in:Sci Rep
Main Authors: Tuekprakhon, Aekkachai, Nakayama, Emi E., Bartholomeeusen, Koen, Puiprom, Orapim, Sasaki, Tadahiro, Huits, Ralph, Luplertlop, Natthanej, Kosoltanapiwat, Nathamon, Maneekan, Pannamas, Ariën, Kevin K., Shioda, Tatsuo, Leaungwutiwong, Pornsawan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773492/
https://ncbi.nlm.nih.gov/pubmed/29348674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19174-8
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