A Heparin Binding Motif Rich in Arginine and Lysine is the Functional Domain of YKL-40

The heparin-binding glycoprotein YKL-40 (CHI3L1) is intimately associated with microvascularization in multiple human diseases including cancer and inflammation. However, the heparin-binding domain(s) pertinent to the angiogenic activity have yet been identified. YKL-40 harbors a consensus heparin-b...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Ngernyuang, Nipaporn, Yan, Wei, Schwartz, Lawrence M., Oh, Dennis, Liu, Ying-bin, Chen, Hongzhuan, Shao, Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2017
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773473/
https://ncbi.nlm.nih.gov/pubmed/29274508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.11.011
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