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PD-L1 Testing in Guiding Patient Selection for PD-1/PD-L1 Inhibitor Therapy in Lung Cancer

Immunotherapy with programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) targeted monoclonal antibodies has dramatically changed the therapeutic and prognostic landscape for several types of malignancy. PD-1 and PD-L1 are immune checkpoint proteins whose binding ultimately result in T cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Diagn Ther
Hauptverfasser: Hunter, Katerina Ancevski, Socinski, Mark A., Villaruz, Liza C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773410/
https://ncbi.nlm.nih.gov/pubmed/29119407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-017-0308-6
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