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A third copy of the Down syndrome cell adhesion molecule (Dscam) causes synaptic and locomotor dysfunction in Drosophila

Down syndrome (DS) is caused by triplication of chromosome 21 (HSA21). It is characterised by intellectual disability and impaired motor coordination that arise from changes in brain volume, structure and function. However, the contribution of each HSA21 gene to these various phenotypes and to the c...

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Bibliografiske detaljer
Udgivet i:Neurobiol Dis
Main Authors: Lowe, Simon A., Hodge, James J.L., Usowicz, Maria M.
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773243/
https://ncbi.nlm.nih.gov/pubmed/29196216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.11.013
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