The mechanisms how heparin affects the tumor cell induced VEGF and chemokine release from platelets to attenuate the early metastatic niche formation

Metastasis is responsible for the majority of cancer associated fatalities. Tumor cells leaving the primary tumor and entering the blood flow immediately interact with platelets. Activated platelets contribute in different ways to cancer cell survival and proliferation, e.g. in formation of the earl...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Ponert, Jan Moritz, Schwarz, Svenja, Haschemi, Reza, Müller, Jens, Pötzsch, Bernd, Bendas, Gerd, Schlesinger, Martin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773218/
https://ncbi.nlm.nih.gov/pubmed/29346400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191303
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