Pik3ca is required for mouse uterine gland development and pregnancy

The PI3K/AKT signaling pathway plays a critical role in the maintenance of equilibrium between cell survival and apoptosis. The Pik3ca gene is mutated in a range of human cancers. It has been found to be oncogenic, and mutations lead to constitutive activation of the PI3K/AKT pathway. The expression...

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Udgivet i:PLoS One
Main Authors: Chang, Hye Jin, Shin, Hee Sung, Kim, Tae Hoon, Yoo, Jung-Yoon, Teasley, Hanna E., Zhao, Jean J., Ha, Un-Hwan, Jeong, Jae-Wook
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773209/
https://ncbi.nlm.nih.gov/pubmed/29346447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191433
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