The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells

BACKGROUND: Cholangiocarcinoma (CCA) has an abundance of tumor stroma which plays an important role in cancer progression via tumor-promoting signals. This study aims to explore the microRNA (miRNA) profile of CCA-associated fibroblasts (CCFs) and the roles of any identified miRNAs in CCA progressio...

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Vydáno v:Mol Cancer
Hlavní autoři: Utaijaratrasmi, Penkhae, Vaeteewoottacharn, Kulthida, Tsunematsu, Takaaki, Jamjantra, Pranisa, Wongkham, Sopit, Pairojkul, Chawalit, Khuntikeo, Narong, Ishimaru, Naozumi, Sirivatanauksorn, Yongyut, Pongpaibul, Ananya, Thuwajit, Peti, Thuwajit, Chanitra, Kudo, Yasusei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773154/
https://ncbi.nlm.nih.gov/pubmed/29347950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0760-x
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