INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia

BACKGROUND: Acute myeloid leukemia (AML) with mutated nucleophosmin (NPM1) has been recognized as a distinct leukemia entity in the 2016 World Health Organization (WHO) classification. The genetic events underlying oncogenesis in NPM1-mutated AML that is characterized by a normal karyotype remain un...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Jin, Hongjun, Yang, Liyuan, Wang, Lu, Yang, Zailin, Zhan, Qian, Tao, Yao, Zou, Qin, Tang, Yuting, Xian, Jingrong, Zhang, Shuaishuai, Jing, Yipei, Zhang, Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773044/
https://ncbi.nlm.nih.gov/pubmed/29343273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0675-9
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