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Assessment of PI3K/AKT/PTEN signaling pathway activity in colorectal cancer using quantum dot-conjugated antibodies

In certain patients with advanced colorectal cancer, loss of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) activity is observed. PTEN is a major gatekeeper gene of the AKT serine/threonine kinase (AKT) signaling pathway responsible for the proliferative activity of cells. The assess...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Waniczek, Dariusz, Śnietura, Mirosław, Lorenc, Zbigniew, Nowakowska-Zajdel, Ewa, Muc-Wierzgoń, Małgorzata
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772923/
https://ncbi.nlm.nih.gov/pubmed/29422975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7392
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