Apelin Ameliorates High Glucose-Induced Downregulation of Connexin 43 via AMPK-Dependent Pathway in Neonatal Rat Cardiomyocytes

Diabetes Mellitus is a common disorder, with increasing risk of cardiac arrhythmias. Studies have shown that altered connexin expression and gap junction remodeling under hyperglycemia contribute to the high prevalence of cardiac arrhythmias and even sudden death. Connexin 43 (Cx43), a major protein...

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Publicado no:Aging Dis
Main Authors: Li, Xiaoting, Yu, Lu, Gao, Jing, Bi, Xukun, Zhang, Juhong, Xu, Shiming, Wang, Meihui, Chen, Mengmeng, Qiu, Fuyu, Fu, Guosheng
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2018
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Orginal Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772859/
https://ncbi.nlm.nih.gov/pubmed/29392082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2017.0426
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