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Profilin Directly Promotes Microtubule Growth Through Residues Mutated in Amyotrophic Lateral Sclerosis

Profilin is an abundant actin monomer binding protein with critical actin regulatory roles in vivo [1,2]. However, Profilin also influences microtubule dynamics in cells, which may be mediated in part through its interactions with Formins that in turn bind microtubules [3,4]. Specific residues on hu...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Biol
Main Authors: Henty-Ridilla, Jessica L., Juanes, M. Angeles, Goode, Bruce L.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772683/
https://ncbi.nlm.nih.gov/pubmed/29129529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.10.002
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