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The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine

Human MCF-7 breast cancer cells were exposed to a Random Positioning Machine (RPM). After 24 hours (h) the cells grew either adherently within a monolayer (AD) or within multicellular spheroids (MCS). AD and MCS populations were separately harvested, their cellular differences were determined perfor...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kopp, Sascha, Sahana, Jayashree, Islam, Tawhidul, Petersen, Asbjørn Graver, Bauer, Johann, Corydon, Thomas J., Schulz, Herbert, Saar, Kathrin, Huebner, Norbert, Slumstrup, Lasse, Riwaldt, Stefan, Wehland, Markus, Infanger, Manfred, Luetzenberg, Ronald, Grimm, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772637/
https://ncbi.nlm.nih.gov/pubmed/29343717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18556-8
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