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Single plasmid systems for inducible dual protein expression and for CRISPR-Cas9/CRISPRi gene regulation in lactic acid bacterium Lactococcus lactis

Lactococcus lactis is a food-grade lactic acid bacterium that is used in the dairy industry as a cell factory and as a host for recombinant protein expression. The nisin-controlled inducible expression (NICE) system is frequently applied in L. lactis; however new tools for its genetic modification a...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Berlec, Aleš, Škrlec, Katja, Kocjan, Janja, Olenic, Maria, Štrukelj, Borut
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772564/
https://ncbi.nlm.nih.gov/pubmed/29343791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19402-1
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