Glucocerebrosidase expression patterns in the non-human primate brain

Glucocerebrosidase (GCase) is a lysosomal enzyme encoded by the GBA1 gene. Mutations in GBA1 gene lead to Gaucher’s disease, the most prevalent lysosomal storage disorder. GBA1 mutations reduce GCase activity, therefore promoting the aggregation of alpha-synuclein, a common neuropathological finding...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Struct Funct
Prif Awduron: Dopeso-Reyes, Iria G., Sucunza, Diego, Rico, Alberto J., Pignataro, Diego, Marín-Ramos, David, Roda, Elvira, Rodríguez-Pérez, Ana I., Labandeira-García, José L., Lanciego, José L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772150/
https://ncbi.nlm.nih.gov/pubmed/28835999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-017-1504-1
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