Glucocerebrosidase expression patterns in the non-human primate brain

Glucocerebrosidase (GCase) is a lysosomal enzyme encoded by the GBA1 gene. Mutations in GBA1 gene lead to Gaucher’s disease, the most prevalent lysosomal storage disorder. GBA1 mutations reduce GCase activity, therefore promoting the aggregation of alpha-synuclein, a common neuropathological finding...

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Detalles Bibliográficos
Publicado en:Brain Struct Funct
Main Authors: Dopeso-Reyes, Iria G., Sucunza, Diego, Rico, Alberto J., Pignataro, Diego, Marín-Ramos, David, Roda, Elvira, Rodríguez-Pérez, Ana I., Labandeira-García, José L., Lanciego, José L.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772150/
https://ncbi.nlm.nih.gov/pubmed/28835999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-017-1504-1
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