The cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development

The enzymes glyoxalase 1 and 2 (Glo1 and Glo2) are found in most eukaryotes and catalyze the glutathione-dependent conversion of 2-oxoaldehydes to 2-hydroxycarboxylic acids. Four glyoxalases are encoded in the genome of the malaria parasite Plasmodium falciparum, the cytosolic enzymes PfGlo1 and Pfc...

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Udgivet i:Microb Cell
Main Authors: Wezena, Cletus A., Alisch, Romy, Golzmann, Alexandra, Liedgens, Linda, Staudacher, Verena, Pradel, Gabriele, Deponte, Marcel
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772037/
https://ncbi.nlm.nih.gov/pubmed/29354648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2018.01.608
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