Effects of co-occurring genomic alterations on outcomes in patients with KRAS-mutant non-small cell lung cancer

BACKGROUND: KRAS mutations occur in approximately 25% of patients with non-small cell lung cancer (NSCLC). Despite the uniform presence of KRAS mutations, patients with KRAS-mutant NSCLC can have a heterogeneous clinical course. Since the pattern of co-occurring mutations may describe different biol...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Arbour, Kathryn C., Jordan, Emmett, Kim, Hyunjae Ryan, Dienstag, Jordan, Yu, Helena A., Sanchez-Vega, Francisco, Lito, Piro, Berger, Michael, Solit, David B., Hellmann, Matthew, Kris, Mark G., Rudin, Charles M., Ni, Ai, Arcila, Maria, Ladanyi, Marc, Riely, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771996/
https://ncbi.nlm.nih.gov/pubmed/29089357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1841
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