A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study

BACKGROUND: The aim of this study was to explore the pharmacokinetic-pharmacodynamic (PK-PD) relationship of metformin on glucose levels after the administration of 250 mg and 1000 mg of metformin in healthy volunteers. METHODS: A total of 20 healthy male volunteers were randomized to receive two do...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Chung, Hyewon, Oh, Jaeseong, Yoon, Seo Hyun, Yu, Kyung-Sang, Cho, Joo-Youn, Chung, Jae-Yong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771593/
https://ncbi.nlm.nih.gov/pubmed/29342199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191258
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki